The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion
نویسندگان
چکیده
Address: 1For 923 at Institut für Pharmakologie und Toxikologie, TU München, Germany, 2Department of Internal Medicine II, Klinikum Rechts der Isar, TU München, Germany, 3Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Germany, 4Department of Pharmacology and Toxicology, Universität Regensburg, Germany and 5Institut für Pharmakologie und Toxikologie, TU München, Germany
منابع مشابه
Heat-stable enterotoxin of Escherichia coli stimulates a non-CFTR-mediated duodenal bicarbonate secretory pathway.
The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is an important pathway for duodenal mucosal bicarbonate secretion. Duodenal biopsies from CF patients secrete bicarbonate in response to heat-stable enterotoxin from Escherichia coli (STa) but not cAMP. To explore the mechanism of STa-induced bicarbonate secretion in CF more fully, we examined the role of CFTR in STa-stimulate...
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